收藏本站
收藏 | 投稿 | 论文排版

Evidence based review of negative pressure wound therapy

Adriana C Panayi  Tripp Leavitt  Dennis P Orgill  
【摘要】:Vacuum-assisted closure, sometimes referred to as microdeformational wound therapy or most commonly negative pressure wound therapy(NPWT), has significantly improved wound care over the past two decades. NPWT is known to affect wound healing through four primary mechanisms(macrodeformation, microdeformation, fluid removal, and alteration of the wound environment) and various secondary mechanisms(including neurogenesis, angiogenesis, modulation of inflammation, and alterations in bioburden) which are described in this review. In addition, the technique has many established uses, for example in wound healing of diabetic and pressure ulcers, as well as burn and blast wounds. This therapy also has many uses whose efficacy has yet to be confirmed, for example the use in digestive surgery. Modifications of the traditional NPWT have also been established and are described in detail. This therapy has various considerations and contraindications which are summarized in this review. Finally, future perspectives, such as the optimal cycling of the treatment and the most appropriate interface material, are touched upon in the final segment. Overall, despite the fact that questions remain to be answered about NPWT, this technology is a major breakthrough in wound healing with significant potential use both in the hospital but also in the community.

知网文化
【相似文献】
中国期刊全文数据库 前13条
1 Pravin J Mishra;Prasun J Mishra;Debabrata Banerjee;;Cell-free derivatives from mesenchymal stem cells are effective in wound therapy[J];World Journal of Stem Cells;2012年05期
2 Karakkattu Vijayan Kavitha;Shalbha Tiwari;Vedavati Bharat Purandare;Sudam Khedkar;Shilpa Sameer Bhosale;Ambika Gopalakrishnan Unnikrishnan;;Choice of wound care in diabetic foot ulcer: A practical approach[J];World Journal of Diabetes;2014年04期
3 裴宪武;王坤正;柏传毅;王强;姜志茹;高登峰;;Clinical experimental study of Arnebia root oil promoting histological change and up-regulating bFGF expression in the wound[J];Journal of Medical Colleges of PLA;2006年01期
4 Alex F CHEN;;Nitric oxide:a newly discovered function on wound healing[J];Acta Pharmacologica Sinica;2005年03期
5 ;A Great Historical Turn in the Burn Medical Science[J];中国烧伤创疡杂志;1989年00期
6 ;Excisional wound splinting model for cutaneous regeneration[J];Science Foundation in China;2014年01期
7 ;On the Principle of Treatment of Burn Wound[J];中国烧伤创疡杂志;1993年02期
8 Santram Lodhi;Singhai AK;;Preliminary pharmacological evaluation of Martynia annua Linn leaves for wound healing[J];Asian Pacific Journal of Tropical Biomedicine;2011年06期
9 吴澂宇 ,田保中 ,朱德安 ,严筱鸣 ,程万里 ,徐帼英;PROPERTIES AND APPLICATIONS OF WOUND PROTECTIVE MEMBRANE MADE FROM FIBROIN[J];苏州丝绸工学院学报;1996年S3期
10 Krishna Murti;Upendra Kumar;;Enhancement of wound healing with roots of Ficus racemosa L.in albino rats[J];Asian Pacific Journal of Tropical Biomedicine;2012年04期
11 ;EXPERIMENTAL STUDY OF THE EFFECT OF MOIST EXPOSED BURN THERAPY/MOIST EXPOSED BURN OINTMENT ON MAINTAINING A PHYSIOLOGICAL MOIST ENVIRONMENT IN BURN WOUND[J];中国烧伤创疡杂志;2001年02期
12 Javad Rafinejad;Kamran Akbarzadeh;Yavar Rassi;Jamasp Nozari;Mohammad Mehdi Sedaghat;Mostafa Hosseini;Hamzeh Alipour;Abdolmajid Ranjbar;Danial Zeinali;;Traumatic myiasis agents in Iran with introducing of new dominant species,Wohlfahrtia magnifica(Diptera:Sarcophagidae)[J];Asian Pacific Journal of Tropical Biomedicine;2014年06期
13 ;[J];;年期
中国重要会议论文全文数据库 前3条
1 ;Wound re-epithelialization results in epidermal stem cells on wound edge[A];中国康复医学会修复重建外科专业委员会第十四次全国学术交流会论文集[C];2004年
2 D. Hashimoto;K.Shinohara;T.Hoshino;;Gasless Colectomy by Area Lifting and Sliding Window——New surgical concept and the development of devices[A];第六次全国大肠癌会议暨中日韩大肠癌会议论文汇编[C];1998年
3 朱慧颖;;The effects of rhGM-CSF on wound healing of gingiva[A];中华口腔医学会第14次全国口腔医学学术会议(2012年会)论文汇编[C];2012年
 快捷付款方式  订购知网充值卡  订购热线  帮助中心
  • 400-819-9993
  • 010-62982499
  • 010-62783978