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Antiviral Activity of Medicinal Plants against Human Coronavirus: a systematic scoping review of in vitro and in vivo experimentations

Parva Namiranian  Omid Sadatpour  Sadegh Azimzadeh Jamalkandi  Mohammad Hossein Ayati  Mehrdad Karimi  
【摘要】:OBJECTIVE: To investigate the in vitro and in vivo studies of natural compounds and medicinal plants with anti-coronavirus activity. METHODS: A systematic review was performed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Animal Research: Reporting of in vivo experiments guidelines to find data for medicinal plants and natural products effective against human coronaviruses in in vitro or in vivo studies. Studies published up to September 6, 2020 were included. Studies(in vitro or in vivo) reporting the effect of medicinal plants and natural products or their derivatives on human coronavirus were included RESULTS: Promising anti-coronavirus effects are seen with different herbal compounds like some diterpenoids, sesquiterpenoids, and three compounds in tea with 3 CLpro inhibiting effect of Severe Acute Respiratory Syndrome Coronavirus(SARS-Co V); Hirsutenone, Six cinnamic amides and bavachinin are PLpro inhibitors and Tanshinones are active on both 3 CLpro and PLpro. Some flavonoid compounds of Citrus fruits act on Immunoregulation and target angiotensin-converting enzyme 2 which is used by SARS-COV for entry. Virus helicase is possibly inhibited by two compounds myricetin and scutellarein. CONCLUSION: This review shows that complementary medicine have the potential for new drug discovery against coronavirus. Further research is needed before definitive conclusions can be made concerning the safety and efficacy of the use of these medicinal plants.

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1 Mariappan Rajan;Prashant Gupta;Awanish Kumar;;Promising Antiviral Molecules from Ayurvedic Herbs and Spices against COVID-19[J];Chinese Journal of Integrative Medicine;2021年04期
2 Deng-hai Zhang;Kun-lun Wu;Xue Zhang;Sheng-qiong Deng;Bin Peng;;In silico screening of Chinese herbal medicines with the potential to directly inhibit 2019 novel coronavirus[J];Journal of Integrative Medicine;2020年02期
3 Da-cheng Hao;Pei-gen Xiao;;Pharmaceutical resource discovery from traditional medicinal plants:Pharmacophylogeny and pharmacophylogenomics[J];Chinese Herbal Medicines;2020年02期
4 Muhammad Shoaib Amjad;Muhammad Arshad;Abdul Saboor;Sue Page;Sunbal Khalil Chaudhari;;Ethnobotanical profiling of the medicinal flora of Kotli,Azad Jammu and Kashmir,Pakistan:Empirical reflections on multinomial logit specifications[J];Asian Pacific Journal of Tropical Medicine;2017年05期
5 ;Computational network pharmacological research of Chinese medicinal plants for chronic kidney disease[J];Science China(Chemistry);2010年11期
6 V Rajashekar;E Upender Rao;Srinivas P;;Biological activities and medicinal properties of Gokhru(Pedalium murex L.)[J];Asian Pacific Journal of Tropical Biomedicine;2012年07期
7 Balayogan Sivasankari;Subburaj Pitchaimani;Marimuthu Anandharaj;;A study on traditional medicinal plants of uthapuram,Madurai District,Tamilnadu,south India[J];Asian Pacific Journal of Tropical Biomedicine;2013年12期
8 Nurbolat Aidarhan;Maiwulanjiang Matnur;Abulimiti Yili;Haji Akber Aisa;;Genuine Medicinal Materials and Resources Development in Xinjiang[J];Medicinal Plant;2020年05期
9 Zhen Xu;Wei-qing He;Chun-sheng Liu;Jian-qiang Kong;;Enzymatic synthesis of myricetin 3-O-galactoside through a whole-cell biocatalyst[J];Chinese Herbal Medicines;2020年04期
10 Ana Lucía Urbizu-González;Octelina Castillo-Ruiz;Guillermo Cristian Guadalupe Martínez-ávila;Jorge Ariel Torres-Castillo;;Natural variability of essential oil and antioxidants in the medicinal plant Turnera diffusa[J];Asian Pacific Journal of Tropical Medicine;2017年02期
11 Han Deng;Shang Liu;Dong Pan;Yi Jia;Ze-Gang Ma;;Myricetin reduces cytotoxicity by suppressing hepcidin expression in MES23.5 cells[J];Neural Regeneration Research;2021年06期
12 CHENG Chun-Song;WANG Can-Jian;LIANG Jie;LAO Chi-Chou;ZHOU Hua;ZHANG Zhi-Feng;;A new approach for identification of medicinal almonds by fourier transform infrared spectroscopy and systematic clustering of characteristic peaks[J];Chinese Journal of Natural Medicines;2017年09期
13 James Huang;Chris Huang;Michael Liebman;;Oxalate contents of commonly used Chinese medicinal herbs[J];Journal of Traditional Chinese Medicine;2015年05期
14 Sadia Shakeel;Zeeshan Ahmed Sheikh;Khan Usmanghani;Nadeem Khalid;Zafar Ali;Somia Gul;Safila Naveed;;Determination of the heavy metal content of Entoban herbal medicinal product[J];Journal of Chinese Pharmaceutical Sciences;2015年11期
15 Garima Singh;Ajit Kumar Passari;Marcy D Momin;Sakthivel Ravi;Bhim Pratap Singh;Nachimuthu Senthil Kumar;;Ethnobotanical survey of medicinal plants used in the management of cancer and diabetes[J];Journal of Traditional Chinese Medicine;2020年06期
16 Yansheng Wang;Yanmin Zhao;Xinnan Liu;Jingyang Li;Jingze Zhang;Dailin Liu;;Chemical constituents and pharmacological activities of medicinal plants from Rosa genus[J];Chinese Herbal Medicines;2022年02期
17 Yuan LIANG;Yi CAI;Xiaotong JING;Xiayu ZHONG;Xiaohui LU;Li LI;;Research Progress on the Efficacy and Chemical Components of Medicinal Taxillus chinensis(DC.) Danser[J];Agricultural Biotechnology;2020年06期
18 Andréa D.Fuzimoto;;An overview of the anti-SARS-CoV-2 properties of Artemisia annua, its antiviral action, protein-associated mechanisms, and repurposing for COVID-19 treatment[J];Journal of Integrative Medicine;2021年05期
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1 Khalid Rahman;;Behavioural and Biochemical Effects of Kaixin-San,a traditional Chinese medicinal empirical formula[A];药学发展前沿论坛及药理学博士论坛论文集[C];2008年
2 Zhongzhen Zhao;Hubiao Chen;Lai Lai Wong;Quanlan Chen;Wenwen Mao;;Chinese Medicinal Microscopic Identification[A];第十四届全国中药和天然药物学术研讨会论文摘要[C];2014年
3 Jl AiJia;LUO HongMei;XU ZhiChao;ZHANG Xin;SONG JingYuan;CHEN ShiLin;;AP2/ERF transcription factors:their structure,function and role in active compound biosynthesis and stress tolerance in medicinal plants[A];第十四届全国中药和天然药物学术研讨会论文摘要[C];2014年
4 关月;Yin Ying;Zhu YanRong;Guo Chao;Wei Guo;Duan JiaLin;Wang YanHua;Zhou Dan;Quan Wei;Weng Yan;Xi MiaoMiao;Wen AiDong;;Dissection of mechanism of a Chinese medicinal formula,Danhong injection therapy for myocardial ischemia/reperfusion injury in vivo and in vitro[A];中华医学会临床药学分会2014年全国学术会议论文汇编[C];2014年
5 ;A critical view on spike recovery for accuracy evaluation of analytical method for medicinal herbs[A];中药与天然药高峰论坛暨第十二届全国中药和天然药物学术研讨会论文集[C];2012年
6 宾晓红;欧贤红;王璐珍;刘瑞;李妙龄;杨艳;曾晓荣;;Dihydromyricetin Inhibits hKv1.5 Channel Expressed in HEK 293 Cells[A];中国生理学会第24届全国会员代表大会暨生理学学术大会论文汇编[C];2014年
7 ;Structural Bioinformatics and Chinese Traditional Medicine Database For Drug Design[A];中国化学会第28届学术年会第14分会场摘要集[C];2012年
8 ;Myricetin attenuates MPP~+-induced cytotoxicity by anti-oxidation and c-JNK modulation in MES23.5 cells[A];中国生理学会第23届全国会员代表大会暨生理学学术大会论文摘要文集[C];2010年
9 Baosheng Liao;Xiaochen Chen;Wenjing Jiao;Lili Wang;Jianping Han;;Identification of Fruit and Seed Medicinal Materials from Traditional Chinese Medicine Market[A];第十四届全国中药和天然药物学术研讨会论文摘要[C];2014年
10 何剑为;王禹;王娜;种晓颖;;Myricetin Prevents Fibrillogenesis of Hen Egg White Lysozyme[A];中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议论文集——专题报告七[C];2014年
11 ;Myricetin attenuates MPP~+-induced cytotoxicity by anti-oxidation and inhibition of MKK4 and JNK activation in MES23.5 cells[A];中国神经科学学会第九届全国学术会议暨第五次会员代表大会论文摘要集[C];2011年
12 Zhongzhen Zhao;Hubiao Chen;Ping Guo;Eric Br;;Chinese Medicinal Identification:An Ⅲustrated Approach[A];第十四届全国中药和天然药物学术研讨会论文摘要[C];2014年
13 Hanwen Chen;Hui Lin;Shujun Xie;Bo Huang;Kelie Chen;Yuequn Niu;Jing Leng;Dajing Xia;Yihua Wu;;Myricetin inhibits NLRP3 inflammasome activation by reducing ROS-dependent ubiquitination of ASC and promoting NLRP3 ubiquitination[A];浙江省免疫学会第六次会员代表大会暨第十一次学术大会论文汇编[C];2018年
14 ;Study on the Chemical Constituents from the Stem of Premna fulva[A];第五届全国化学生物学学术会议论文摘要集[C];2007年
15 ;Ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry based chemical profiling approach to rapidly reveal chemical transformation of sulfur-fumigated medicinal herbs,a case study on white ginseng[A];中药与天然药高峰论坛暨第十二届全国中药和天然药物学术研讨会论文集[C];2012年
16 ;Study on the Cold and Hot Properties of Medicinal Herbs by Thermotropism in Mice Behavior[A];经济发展方式转变与自主创新——第十二届中国科学技术协会年会(第三卷)[C];2010年
17 Tsutomu HATANO;;Structures of Tannins and Related Polyphenols in Medicinal Plants and Their Biological and Pharmacological Effects[A];第八届全国药用植物及植物药学术研讨会论文集[C];2009年
18 ;mTOR and MAPK signal pathway involved in cryptotanshinone inhibiting cancer cell growth[A];全国中药药理学会联合会学术交流大会论文摘要汇编[C];2012年
19 李芳;;A case with toxic encephacopathy induced by radix sophorae tonkinensis[A];中华医学峰会暨中华医学会神经病学分会第八届全国中青年神经病学学术会议论文汇编[C];2015年
20 Ku TC;Hsieh WT;Wang HD;Nishibe S;Seo S;Kwan CY;;Dual vascular effects of luobuma:an indigenous medicinal herb in Xingjian,China[A];第七届海峡两岸心血管科学研讨会论文集[C];2009年
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