【摘要】:正Objective To observe the effect of Bushen Shuji Granule(BSG)on mRNA and protein expressions of Smad-4 and BMP-4 in human Bone marrow mesenchymal stem cells.Methods Human bone marrow mesenchymal stem cells were in vitro cultured,and then divided into a blank control group,the Western medicine group,the model group,high,mid,and low dose BSG groups.Then they were induced to osteoblasts.mRNA and pro-