收藏本站
收藏 | 投稿 | 手机打开
二维码
手机客户端打开本文

Configuration Confirmation of Euphorbia Factor L_1 by Single-crystal X-ray Diffraction

焦威  郁开北  鲁润华  
【摘要】:A 6,(17)-epoxylathyrol diterpenoid((2S*3S*4R*5R*6S*9S*11S*15R*)-5,15-diacetoxy-3-phenylacetoxy-14-oxolathyra-6(17),(12E)-diene-6(17)-epoxide) was isolated from the seeds of Euhporbia lathyris L.Its configuration was puzzled because of the incomplete X-ray results reported before.In this work,the atom connectivity and configuration were confirmed by single-crystal X-ray diffraction together with ESI-MS,1H-,and 13C-NMR spectroscopy.The compound crystallizes in monoclinic,space group P21 with a = 11.386(1),b = 8.2839(7),c = 17.192(2) ,β = 108.305(2)°,Z = 2,V = 1539.5(2) 3,C32H40O8,Mr = 552.64,Dc = 1.192 g/m3,F(000) = 592,μ(MoKα) = 0.085 mm-1,T = 293(2) K,the final R = 0.0398 and wR = 0.0950 for 2057 observed reflections with I 2σ(I).The molecule shows a tricyclic terpenoid skeleton,consisting of fused five-,eleven-and three-membered rings.The configuration at C(5) is R* and that at C(6) S*.

知网文化
 快捷付款方式  订购知网充值卡  订购热线  帮助中心
  • 400-819-9993
  • 010-62982499
  • 010-62783978