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功能磁共振成像技术在轻微肝性脑病应用中的研究进展

葛岩松  王培源  
【摘要】:肝性脑病(hepatic encephalopathy,HE)是肝硬化失代偿期常见且较为严重的并发症之一,对中枢神经系统产生严重的损害。轻微肝性脑病(minimal hepatic encephalopathy,MHE)是HE中的一个亚型,早期诊断与干预对阻止MHE向显性肝型脑病(overt hepatic encephalopathy,OHE)发展及其预后具有重要的临床意义。随着功能磁共振成像技术(functional magnetic resonance imaging,fMRI)的不断发展,fMRI不仅可以清晰的显示大脑形态学结构的变化,更能全面了解脑功能及其代谢变化情况,在早期诊断轻微肝性脑病上发挥着重要作用。作者对目前fMRI在MHE的应用进展进行综述。

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