《World Journal of Gastroenterology》2008年19期 加入收藏    获取最新 
 Managing injuries of hepatic duct confluence variants after major hepatobiliary surgery:An algorithmic approach
 Georgios Fragulidis;Athanasios Marinis;Andreas Polydorou;Christos Konstantinidis;Georgios Anastasopoulos;John Contis;Dionysios Voros;Vassilios Smyrniotis
 　　AIM:To investigate injuries of anatomy variants of hepatic duct confluence during hepatobiliary surgery and their impact on morbidity and mortality of these procedures. An algorithmic approach for the management of these injuries is proposed. METHODS:During a 6-year period 234 patients who had undergone major hepatobiliary surgery were retrospectively reviewed in order to study postoperative bile leakage. Diagnostic workup included endoscopic and magnetic retrograde cholangiopancreatography (E/MRCP), scintigraphy and fistulography. RESULTS:Thirty (12.8%) patients who developed postoperative bile leaks were identified. Endoscopic stenting and percutaneous drainage were successful in 23 patients with bile leaks from the liver cut surface. In the rest seven patients with injuries of hepatic duct confluence, biliary variations were recognized and a stepwise therapeutic approach was considered. Conservative management was successful only in 2 patients. Volume of the liver remnant and functional liver reserve as well as local sepsis were used as criteria for either resection of the corresponding liver segment or construction of a biliary-enteric anastomosis. Two deaths occurred in this group of patients with hepatic duct confluence variants (mortality rate 28.5%). CONCLUSION:Management of major biliary fistulaethat are disconnected from the mainstream of the biliary tree and related to injury of variants of the hepatic duct confluence is extremely challenging. These patients have a grave prognosis and an early surgical procedure has to be considered.
【作者单位】：Second Department of Surgery Areteion University Hospital;Athens Medical School;University of Athens;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;76 Vassilisis Sofia's Ave.;Athens 11528;Greece;76 Vassilisis Sofia's Ave.;Athens 11528;Greece;76 Vassilisis Sofia's Ave.;Athens 11528;Greece;76 Vassilisis Sofia's Ave.;Athens 11528;Greece;76 Vassilisis Sofia's Ave.;Athens 11528;Greece;76 Vassilisis Sofia's Ave.;Athens 11528;Greece;76 Vassilisis Sofia's Ave.;Athens 11528;Greece;76 Vassilisis Sofia’s Ave.;Athens 11528;Greece
【分类号】：R657.4
【DOI】：CNKI:SUN:ZXXY.0.2008-19-016
【正文快照】：
　　INTRODUCTION Dissection of the biliary tract constitutes the most crucial step in liver resections and every effort should aim to secure integrity and normal bile flow of the liver remnant. However, up to 40% of the patients are lacking the conventional b…
 
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 Managing injuries of hepatic duct confluence variants after major hepatobiliary surgery:An algorithmic approach
 Georgios Fragulidis;Athanasios Marinis;Andreas Polydorou;Christos Konstantinidis;Georgios Anastasopoulos;John Contis;Dionysios Voros and Vassilios Smyrniotis;Second Department of Surgery;Areteion University Hospital;Athens Medical School;University of Athens;76 Vassilisis Sofia’s Ave.;Athens 11528;Greece
 　AIM:To investigate injuries of anatomy variants of hepatic duct confluence during hepatobiliary surgery and their impact on morbidity and mortality of these procedures. An algorithmic approach for the management of these injuries is proposed. METHODS:During a 6-year period 234 patients who had undergone major hepatobiliary surgery were retrospectively reviewed in order to study postoperative bile leakage. Diagnostic workup included endoscopic and magnetic retrograde cholangiopancreatography (E/MRCP), scintigraphy and fistulography. RESULTS:Thirty (12.8%) patients who developed postoperative bile leaks were identified. Endoscopic stenting and percutaneous drainage were successful in 23 patients with bile leaks from the liver cut surface. In the rest seven patients with injuries of hepatic duct confluence, biliary variations were recognized and a stepwise therapeutic approach was considered. Conservative management was successful only in 2 patients. Volume of the liver remnant and functional liver reserve as well as local sepsis were used as criteria for either resection of the corresponding liver segment or construction of a biliary-enteric anastomosis. Two deaths occurred in this group of patients with hepatic duct confluence variants (mortality rate 28.5%). CONCLUSION:Management of major biliary fistulaethat are disconnected from the mainstream of the biliary tree and related to injury of variants of the hepatic duct confluence is extremely challenging. These patients have a grave prognosis and an early surgical procedure has to be considered.
【Keyword】：Biliary aberrations;Bile duct injury;Postope- rative bile leakage;Hepatic duct confluence;Hepatectomy
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