【摘要】：[Objectives] To observe the clinical effect of dark tea with pericarpium citri reticulateae combined with metformin for type 2 diabetes mellitus. [Methods] A total of 80 cases of patients with type 2 diabetes mellitus were randomly divided into the control group and the observation group with 40 cases in each group. The control group was given metform for treatment, and the observation group was given dark tea with pericarpium citri reticulateae combined with metformin for treatment. The two groups were continuously treated for 12 weeks. The indexes of patients were observed and recorded,such as the body mass index(BMI), abdominal circumference(AC), hemoglobin A1 c(HbA1 c), fasting blood glucose(FBG), postprandial 2 h blood glucose(P2 hBG),uric acid(UA),total cholesterol(TC),and triglyceride(TG). The incidence of adverse reactions during the treatment period and the patient satisfaction for treatment in the two groups were counted. [Results] After treatment, the FBG, P2 hBG and HbA1 c in the two groups were decreased when compared with those before treatment(P0.05) and the decrease of the above indexes in the observation group was more significant than that in the control group(P0.05). After treatment,the BMI,AC,UA,TC and TG in the observation group were decreased more significantly when compared with those before treatment and those in the control group after treatment, differences were statistically significant(P0.05). The above indexes in the control group did not change significantly before and after treatment(P0.05). The incidence of adverse reactions was 2.5% in the observation group and 5.0% in the control group,the difference was not statistically significant(P0.05). The patient satisfaction was 97.5% in the observation group and 55.0% in the control group, the difference was significant(P0.05). [Conclusions] The curative effect of dark tea with pericarpium citri reticulateae combined with metformin for type 2 diabetes mellitus is better than that of western medicine alone and has no obvious adverse reactions, thus it is worthy of clinical promotion and application.