| | | | | 芳基硼酸与芳香卤化物的缩合反应 | | | 谢颂凯,马武平,涂敬仁,黄文洪 | | | 研究了一种新的芳基—芳基偶合反应,取代芳基硼酸与芳香卤化物在零价钯络合物的催化下顺利地发生芳香偶合反应,对一系列在芳环上有推电子取代基的化合物的考察表明,芳香卤化物上的取代基的电子效应不影响偶合反应,它们处于邻位时,也不产生位阻效应,因此,本偶合反应在合成联芳香化合物中有广泛的应用前景。本文也探讨了中间体的合成及偶合反应的条件。
【作者单位】：佛山大学
(谢颂凯;马武平);中山大学
(涂敬仁);中山大学(黄文洪)
【关键词】：芳香偶合反应;芳基硼酸;有机合成反应
【DOI】：cnki:ISSN:1008-018X.0.1990-04-000
【正文快照】：
对轴不对称联芳香化凸物的研究,包括它在不对称有机反应和合成上的应用,日益引起有讥化学界的重视〔1〕.诊研乡0z域中山。个突出课题是寻找出能)&广泛应用的合成联芳香化合物的方法.目前常用的儿种芳基一芳上引冯合反应在合成中尚不能广泛地应用.随着对过渡金属有机化合物合成和性质的研究,它作为芳香化合物渴合试剂的可能性日益显示出来,其中零价主巴配合物是最有实际用途的一类化合物. A.S。ZZki[刀用苯基硼酸在硷性条件下和四(三苯暇)把(O)的催化作用下分别与几个取代澳苯发生偶合反工迂,所得驼刁<衍生物的产率。般很好.此后,R.B.Mil… | | |  推荐 CAJ下载  PDF下载 | | | CAJViewer7.0阅读器支持所有CNKI文件格式，AdobeReader仅支持PDF格式 | | | | THE CONDENSATION OF ARYLBORONIC ACIDS WITH VARIOUS SUBSTITUTED PHENYLBROMIDES | | | Xie Songkai Ma Wuping Tu Jinren Huang Wenhong ( Foshan University ) ( Zhongshan University ) | | | The article studied a novel aryl-aryl coupling reaction. It stated that nnder the catalysis of tetra( triphenyl phosphine ) pal ladium ( 0 ),subs ti tu- ted arylboronic acids were smoothly reacted with bromobenzenes to carry out the cross-coupling reaction. Biaryls could be produced as expected in the reaction of arylboronic acid with bromobenzene, both of which were substituted by electron-donating groups in various positions,as shown in Table 1. No electronic and/or steric effects could obviouslybe detected in these coupling reactions. The physical and spectoscopic data of coupling products were listed in Table 2. From above results, we conclude that this reactbon would be widely applied to the synthesis of biaryl compounds. Moreover, reaction conditions in synthesis of intermediates and in copling were also studied.
【Keyword】：aryl-aryl coupling, arylboronic acid, organic synthesis |
| | | | | | 1 | 谢颂凯,马武平,涂敬仁,黄文洪; 芳基硼酸与芳香卤化物的缩合反应 [J];佛山科学技术学院学报(社会科学版); 1990年04期; 4-10 | | 2 | 耐热涂料 [J];涂料技术与文摘; 2004年05期; 72-73 |
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