收藏本站
《World Journal of Hepatology》 2017年01期
收藏 | 投稿 | 手机打开
二维码
手机客户端打开本文

Ultrasound shear wave elastography and liver fibrosis: A Prospective Multicenter Study

Joyce Anyona Sande  Suleman Verjee  Sudhir Vinayak  Farin Amersi  Munir Ghesani  
【摘要】:AIM To assess the accuracy of shear wave elastography(SWE) alone and in combination with aminotransferase platelet ratio index(APRI) score in the staging of liver fibrosis.METHODS A multicenter prospective study was conducted to assess the accuracy of SWE(medians) and APRI to predict biopsy results. The analysis focused on distinguishing the different stages of liver disease, namely, F0 from F1-4, F0-1 from F2-4, F0-2 from F3-4 and F0-3 from F4; F0-F1 from F2-F4 being of primary interest. The area under the receiver operating characteristic(AUROC) curve was computed using logistic regression model. The role of age, gender and steatosis was also assessed.RESULTS SWE alone accurately distinguished F0-1 from F2-4 with a high probability. The AUROC using SWE alone was 0.91 compared to 0.78 for using the APRI score alone.The APRI score, when used in conjunction with SWE, did not make a significant contribution to the AUROC. SWE and steatosis were the only significant predictors that differentiated F0-1 from F2-4 with an AUROC of 0.944.CONCLUSION Our study validates the use of SWE in the diagnosis and staging of liver fibrosis. Furthermore, the probability of a correct diagnosis is significantly enhanced with the addition of steatosis as a prognostic factor.

【相似文献】
中国期刊全文数据库 前10条
1 史晓林,杨爱民,李凤芝;AN ANALYSIS ON THE THERAPEUTIC EFFECT OF ACUPUNCTURE AT SANYINJIAO POINT FOR TREATMENT OF 120 CASES OF PRIMARY DYSMENORRHEA[J];World Journal of Acupuncture-Moxibustion;1995年03期
2 ;Meta-analysis on inoperable pancreatic cancer: A comparison between gemcitabine-based combination therapy and gemcitabine alone[J];World Journal of Gastroenterology;2006年43期
3 Yubo Li;Yuxiu Sun;Xueling Ma;Xiaoxing Xue;Wenting Zhang;Zhiqian Wu;Yulin Ouyang;Jianxin Chen;Weiming Wang;Shuzhen Guo;Wei Wang;;Effects of Sini San used alone and in combination with fluoxetine on central and peripheral 5-HT levels in a rat model of depression[J];Journal of Traditional Chinese Medicine;2013年05期
4 ;Cor pulmonale[J];China Medical Abstracts;1995年02期
5 陈廷祚;Gaojushen:a novel anti-cancer drug prepared from SEC superantigen[J];微生物学免疫学进展;2005年02期
6 Yu Xuan Koo;Daniel SW Tan;Iain BH Tan;Richard Quek;Miriam Tao;Soon Thye Lim;;“Anti-HBc alone” in human immunodefi ciency virus-positive and immuno-suppressed lymphoma patients[J];World Journal of Gastroenterology;2009年30期
7 M~aTeresa Pérez-Rodríguez;Bernardo Sopea;Manuel Crespo;Alberto Rivera;Teresa González del Blanco;Antonio Ocampo;César Martínez-Vázquez;;Clinical significance of"anti-HBc alone"in human immunodeficiency virus-positive patients[J];World Journal of Gastroenterology;2009年10期
8 李熙;;Effects of low dose Glibenclamide on secondary damage after acute spinal cord injury in rats[J];China Medical Abstracts(Surgery);2011年02期
9 Koji Yamaguchi;Munechika Enjoji;Manabu Nakashima;Makoto Nakamuta;Takashi Watanabe;Masao Tanaka;;Novel serum tumor marker, RCASl, in pancreatic diseases[J];World Journal of Gastroenterology;2005年33期
10 宋堃;;Meta-analysis of the efficacy between gemcit-abine-alone and gemcitabine-based chemotherapy applied to advanced pancreatic cancer[J];China Medical Abstracts(Surgery);2012年01期
中国重要会议论文全文数据库 前9条
1 ;Who are we ?Where are we from? Are we alone ?[A];中国天文学会2004年学术年会论文集[C];2004年
2 ;Efficacy and safety of MAB versus castration alone in the treatment of advanced Prostate cancer[A];第十六届全国泌尿外科学术会议论文集[C];2009年
3 Martinez-Castillo;;Pars plana vitrectomy alone without postoperative tamponade agent[A];中国眼底病论坛·全国眼底病专题学术研讨会论文汇编[C];2008年
4 郑向鹏;Beth A.Goins;Cristina Santoyo;Gary D Fullerton;;Characterization of Microbubble-Liposomes for[A];中华医学会第16次全国放射学学术大会论文汇编[C];2009年
5 Xinchun JIN;Jie LIU;Ke J.LIU;Gary A.ROSENBERG;Yi YANG;Wenlan LIU;;Normobaric hyperoxia combined with minocycline provides greater neuroprotection than either alone in transient focal cerebral ischemia[A];中国神经科学学会第十届全国学术会议论文摘要集[C];2013年
6 Linping Cao;Jian Wu;Zhen Lv;Ze Qian;Chengli Du;Haiyang Xie;Lin Zhou;Shusen Zheng;;Transarterial chemoembolization in combination with sorafenib in the treatment of intermediate-advanced hepatocellular carcinoma:a meta-analysis[A];2013中国器官移植大会论文汇编[C];2013年
7 金洁;;MDS的治疗(英文)[A];第十一届全国红细胞疾病学术会议暨学习班论文汇编[C];2007年
8 ;Proton Magnetic Resonance Spectroscopy of Metastatic tumors[A];2011中华医学会神经外科学学术会议论文汇编[C];2011年
9 ;Antiangiogenic Effect of Metronomic Temozolomide Combined with Ginsenoside Rg3 on C6 Xenograft Rats Model[A];首届浙赣两省肿瘤研究交流会论文汇编[C];2012年
 快捷付款方式  订购知网充值卡  订购热线  帮助中心
  • 400-819-9993
  • 010-62791813
  • 010-62985026