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《Science China(Life Sciences)》 2018年05期
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Synaptobrevin-2 facilitates the trafficking and function of atrial SK2 channel

Tao Li  Xuehui Fan  Yiyan Yu  Linlin Chen  Wenjun Huang  Yan Yang  Jimin Cao  Xiaorong Zeng  Xiaoqiu Tan  
【摘要】:正Dear Editor,Small conductance Ca2+-activated potassium (SK) channels are widely expressed in various tissues and play a unique role in regulating cell function by integrating cytosolic Ca2+ levels and membrane potential (Adelman et al., 2012). Xu et al. first identified SK channels in the heart and found that SK channels, particularly the SK2 channel, are preferentially expressed in human and mouse atrial myocytes but not in ventricular myocytes (Xu et al., 2003). This suggests that the SK

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